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All three patients were receiving pioglitazone 30 mg (0.9%) in the 24-week add-on to insulin trial

Trial reports vary, with roughly 4 percent to 14 percent of participants reporting headaches, depending on the dose and study population

Insulin has been reported to inhibit GLP-1 release, indicating a feedback regulation of GLP-1 secretion

For a bit of added nutrition, you can add small amounts of dips or toppings to these plain carbs, like hummus, nut butter, ricotta, mashed avocado, or cheese

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