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Treatments for Insulin Resistance If insulin resistance is the primary concern, alternative supplements include inositol and berberine
Both approaches produce good results
ChalasaniNYounossiZLavineJECharltonMCusiKRinellaMet al
Rather than binding to a single receptor like most drugs, this peptide influences numerous biological pathways simultaneously
Trimethylamine N -Oxide: A link among diet, gut microbiota, gene regulation of liver and intestine cholesterol homeostasis and HDL function
Cardiovascular Outcomes Liraglutide (LEADER trial): 13% reduction in major adverse cardiovascular events (MACE) in patients with Type 2 diabetes and high cardiovascular risk Statistically significant cardiovascular protection Semaglutide (SELECT trial): 20% reduction in MACE in patients with obesity and established cardiovascular disease Studied specifically for cardiovascular outcomes in obesity (not just diabetes) Both medications provide cardiovascular protection, but semaglutides evidence is more recent, more robust, and specifically applicable to patients with obesity regardless of diabetes status
