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Our data further suggest that the transsulfuration pathway in SAA metabolism, particularly CBS-mediated production of Ctt and H 2 S, may be one of the major effectors of HNF4-mediated EMT suppression in liver cancer

10.1016/S1570-0232(03)00399-4 Summary Keywords acetaminophen, reactive metabolite, covalent binding, glutathione S -transferase, bottom-up proteomics, data-dependent acquisition, high-resolution tandem mass spectrometry, multiple reaction monitoring Citation Geib T, Lento C, Wilson DJ and Sleno L (2019) Liquid Chromatography-Tandem Mass Spectrometry Analysis of Acetaminophen Covalent Binding to Glutathione S -Transferases

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The animal experiments conformed to the Guide for the Care and Use of Laboratory Animals