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Semaglutide is available as both tablets and injections, while tirzepatide is only available as an injection

And here, with this, thats not really happening, Davis said

But when taken as prescribed, both options support weight-loss efforts

For patients first prescribed an AOM in December 2024, 50.5% filled a GLP-1 RA within 60 days

The Institute for Clinical and Economic Review (ICER) in 2025 noted that price reductions and long-term benefits have improved GLP-1 cost-effectiveness relative to older assumptions ( [70] ), yet insurers still face high absolute spend

These include chronic pain, frequent Tylenol use, drinking alcohol regularly, medication interactions, or a history of liver issues