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(Frontiers in Pharmacology, 2022) reports a half-life under 30 minutes after IM or IV administration in rodent and dog models, which is why split-dose schedules appear in the literature
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Across the panel of 84 mRNAs screened in the array, eight were induced or repressed two folds or more in the samples of BPC-157 treatment compared with that of controls
The discrepancy in the reports of p53 expression in keloids 5,26,27 suggests that the regulatory functions of p53 in keloid fibroblasts depends on activities rather than expression levels of p53