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The most commonly reported side effects for both agents are gastrointestinal, including nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
AOD-9604 offers a distinct, IGF-1-independent lipolysis mechanism worth studying in its own right
injection to be used by, or under the supervision of, a veterinary surgeon
These cells can become cholesterol-filled foam cells, an important feature of developing atherosclerotic plaque
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Our meta-analysis of 49 murine single-cell datasets revealed that Mtnr1a transcripts were detectable in the lung, whereas Mtnr1b was largely absent ( Supplementary Figure 3A ), whereas in a similar analysis of over 250 human datasets, both Mtnr1a and Mtnr1b were detected ( Supplementary Figure 3B )
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