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By Kimberly Ferrero GLP-1 medications (Glucagon-like peptide-1 receptor agonists) did not begin their clinical lives as weight-loss drugs

As with previous dual agonists, the main side effects were gastrointestinal and occurred mostly during the initial dose escalation

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Richard goodman: Glp-1 discoverer In the 1970s, scientists in Boston and California started a revolution in genetic research

For someone at 240 pounds, that gap represents an additional 14 to 15 pounds of fat loss

The combined primary endpoint of death from cardiovascular disease, nonfatal myocardial infarction, or nonfatal stroke occurred in 569 (6.5%) of patients in the semaglutide group versus 701 (8.0%) of patients in the placebo group, yielding a significant hazard ratio of 0.8 for a 20% relative risk reduction