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Pharmaceutical companies are addressing these challenges through combination regimens and novel formulations aimed at improving tolerability
The gastrointestinal side effects that appeared during dose increases typically begin resolving
Vitamin B12 is essential for healthy nerve function, red blood cell formation, and DNA synthesis
Do not minimize them to avoid having your dose reduced
The primary clinical anchor in the published literature is a double-blind, placebo-controlled RCT by Leyden and colleagues, published in the Archives of Dermatology in 2001
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