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& Voedisch, B

Tirzepatide is unique as a dual GIP and GLP-1 receptor agonist

And reduction rate between (-5.6,-6.7 mm Hg) in a 26 week study of liraglutide in combination with Metformin and Rosiglitazone compared to (-1.1 mm Hg)placebo and also with no difference in diastolic blood pressure [12]

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GLP-1 treatment led to ~20% lean mass loss

Cardiomyocyte-derived CXCL12 is not involved in cardiogenesis but plays a crucial role in myocardial infarction