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Human clinical-trial data (Phase 1/2 studies in wound healing, cardiac injury, and dry eye) exist only for a different, full-length recombinant thymosin beta-4 product, not for the short synthetic fragment marketed as TB-500, so no completed published human trial has evaluated TB-500 specifically for muscle, tendon, or joint recovery
Thereby, all these studies point towards a prognostic impact of iron overload markers as ferritin and hepcidin for fungal and bacterial infections as well as for the occurrence of GvHD
The cellular antioxidant capacity to defend against oxidative stress is regulated by the synthesis and use of GSH