Weight loss is certainly an added bonus and definitely a driving factor behind putting people without any cardiovascular disease or obesity-related comorbidities on them, but I think about them all the time in regard to optimizing my patients cardiovascular risk profile. While clinical trials havent yet uncovered a reduction in hard CV outcomes in patients without diabetes, many believe those data will be here soon
Individuals with heart disease or unmanaged hypertension should refrain from taking PT-141, as it may elevate blood pressure
They may provide significant cardiovascular benefits, as many RA and PsA patients are at increased risk for heart disease
Patients often experience significant reductions in food intake, which can lead to insufficient energy substrate availability, particularly if nutritional quality is poor
S., Deen, W
demonstrated greater survival, preserved LV function, decreased myocyte apoptosis and reduced caspase-3 activation on chronic GLP-1 infusion in spontaneously hypertensive, heart failure prone rats [74]