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Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for the treatment of type 2 diabetes mellitus and chronic weight management
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For example, a study published in October 2023 found that the use of GLP-1 drugs for weight loss was associated with an increased risk for pancreatitis, gastroparesis, and bowel obstruction
In clinical trials, Ozempic lowered fasting blood sugar levels by 22% compared to placebo after 12 weeks of treatment
Neutrophils from patients with autoinflammatory and autoimmune diseases had markedly enhanced ROS levels, most notably in RA SF
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