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Initial discussions should also include issues around lifestyle (nutrition, weight loss, and physical activity) and the possible treatment of obesity, such as using the American Association of Clinical Endocrinologists Obesity Treatment Algorithm, which may include obesity pharmacotherapy [14]

GLP-1 RAs are contraindicated during pregnancy due to limited safety data and potential embryofetal risk

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It showed that different ways of giving vitamin B12, like shots, pills, or under the tongue, work well

2.3 Interaction of GIP and GLP-1 in the incretin effect Studies in rodents (46) and canines (47) have delineated the existence of a proximal-distal incretin loop