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Physiol Rev 95:513548 Sisley S, Gutierrez-Aguilar R, Scott M, D'Alessio DA, Sandoval DA, Seeley RJ (2014) Neuronal GLP1R mediates liraglutides anorectic but not glucose-lowering effect

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The fatty-acid structure surrounding semaglutide might have prevented it from being able to penetrate certain brain regions, such as the hippocampus, which controls memory and cognitive function

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I even had one lady with chronic pain who after two courses no longer needed to walk with a stick because she felt so much better*

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