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ABBV-514 is an anti-chemokine C-C motif receptor 8 (CCR8) antibody that is being investigated for the treatment of relapsed non-small cell lung cancer (NSCLC) and head and neck squamous cell carcinoma (HNSCC) as a single agent and in combination with a PD-1 inhibitor

In vivo antitumor efficacy assessment When the tumor volumes reached approximately 100 mm, twenty female BALB/c nude mice bearing 143B tumors were randomly assigned into four groups

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