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Self-administering unregulated injectable substances carries serious risks, including infection, embolism, and systemic toxicity
GLP-1s work by mimicking a natural hormone called GLP-1 (glucagon-like peptide-1), which is released in the gut after eating
Larsen, Fledelius, Knudsen,Tang-Christensen
Do not freeze reconstituted vials
Protein turnover releases - N -trimethyllysine, which is hydroxylated by - N -trimethyllysine hydroxylase in a reaction requiring Fe 2+ and ascorbate, producing -hydroxy-- N -trimethyllysine
Table 1 Oral based GLP-1 agents
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