PEA is thought to work by supporting the inflammatory response through the PPAR-a receptor, COX-2 and through effects on NF-kappaB signaling while also by restoring balance in the endocannabinoid system
As you spent most of your time at home lack of exercise and sedentary lifestyle might have lead to excessive weight gain
Autonomic changes in ME/CFS are likely to cause an overall effect of vasoconstriction and resultant hypoperfusion (58), which is central to the pathology of ME/CFS (183) ( Figure 8 )
For instance, vitamin b1 is nerve energizer, vitamin b6 helps in nerve signal transmission, while as vitamin b12 work as nerve generator
Aside from Vitamin B12, it contains choline, methionine, and inositol
Early studies and user feedback suggest a daily dosage of 50mg to 150mg