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The primary effect is an overall increase in total caloric consumption

Histological Evaluations (HE) and Immunohistochemistry (IHC) Gastric tissue samples fixed in paraformaldehyde were embedded in paraffin, then dyed with hematoxylin and eosin (H&E)

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Replacement of Tyr110 in recombinant Y110A decreased both k cat app and 1/ values for the disulfide substrate and GSH in the GSSCys and HEDS assay (Supplementary Figs 18 and 19)