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Individual spells of semaglutide nausea last an average of eight days

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What GLP-1 Drugs Do GLP-1 receptor agonists work by mimicking the glucagon-like peptide-1 hormone, which regulates blood sugar, increases the feeling of fullness, and slows stomach emptying resulting in weight loss and improved glucose control

In a 2025 study published in Obesity Medicine , 52% of patients who discontinued GLP-1 therapy cited adverse effects as the main reason

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