Tolerance and autoimmunity
Short-chain fatty acid receptor and its contribution to glucagon-like peptide-1 release
For patients who are needle-averse, who have difficulty adhering to strict dosing windows, or whose weight management goals do not require reductions of 20% or more, an oral GLP-1 weight loss regimen may be a well-matched and more sustainable choice
Previous clinical trials have demonstrated that weight loss has been associated with significant reductions in cardiovascular disease, sleep disorders and diabetes and a host of other health problems, including back, hip and knee pain
Scientific References NG28 Type 2 diabetes in adults: visual summary choosing medicines for first-line and further treatment
Regarding GLP-1 medications and the question of purported SMM loss, there is a paucity of published human RCT data explicitly and thoroughly addressing the question with valid probative methods