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The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure

selective lipid metabolism modulation independent of GH receptor

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Relative telomere length and mitochondrial DNA copy number variation with age: association with plasma folate and vitamin B12. Mitochondrion 51 (2020): 79-87.

PMID: 41599884 7 A pilot study comparing the pharmacokinetics of injectable cyanocobalamin and hydroxocobalamin associated with a trace mineral injection in cattle

It functions as an osmolyte that helps regulate intracellular water content and electrolyte balance, thereby maintaining proper cell hydration and volume