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It works by stimulating insulin secretion after a meal, reducing glucagon secretion, delaying gastric emptying, causing a reduction in hunger and food intake, slowing the release of food from the stomach, and increasing feelings of fullness after eating(2 Trusted Source Weight Loss and Maintenance Related to the Mechanism of Action of Glucagon-Like Peptide-1 Receptor Agonists Go to source)

Clinicians may tailor the start dose for older adults, people with kidney or liver concerns, or those taking other drugs that affect digestion

339 When GLP-1 binds to GLP-1R, it activates the cAMP signaling pathway, leading to increased cAMP levels

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If it needs help, gently swirl or roll the vial

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