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Regarding the inclusion of preprints, its inclusion was carefully justified to reflect cutting-edge developments, and we emphasize that its preliminary nature does not detract from the overall evidence base

[7] Aroda VR, et al

G.BarbarinoA.HautauH.NabeelaS.GebremariamT.et al

Accumulating evidence shows that inhibitors of glutamine metabolism, such as V-9302, JHU-083, and CB-839, elicit stronger antitumor effects when used in combination with immune checkpoint inhibitors 144,145,146 (Fig

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