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Obesity medications may counter the effects of metabolic adaptation and prevent weight regain

This can change the clinical calculus for HRT dosing

Some GLP-1 RAs (like semaglutide) might even interfere with certain lab tests for B12, so doctors need to be aware of that

Do not use if damaged Keep medication out of reach of children Place used needles in an NHS-approved sharps container and follow local guidance for pen disposal By following these storage recommendations, you can ensure that each dose of Wegovy delivers the intended therapeutic benefit

Women with polycystic ovary syndrome (PCOS) represent a particularly relevant population

However, rapid weight loss may temporarily alter hormone levels and energy, with net effects varying by individual