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Pregnant or breastfeeding women are typically advised against use due to insufficient research
People taking medications that interfere with B12 absorption, including metformin or long-term acid-reducing medications, often benefit from injections
Older adults : As we age, our bodies become less efficient at absorbing nutrients like B12, and deficiency is more common after age 60
The NHS lists the common symptoms as: Persistent tiredness, breathlessness and a lack of energy Pins and needles, numbness or tingling in the hands and feet A sore, red tongue and mouth ulcers Problems with memory, concentration and mood Pale or slightly yellow-tinged skin If several of these sound familiar and you are on long-term metformin, that is a good reason to ask your GP for a B12 blood test rather than to book an injection straight away
Key Research Applications Targeted lipolysis: Investigators study the ability of this fragment to stimulate fat breakdown in adipose tissue without influencing blood glucose or IGF-1 levels