Jan 2006;5(1):29-32
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Reiner 45 found that it was difficult to measure the rate of dilution of sclerosing solutions in the rabbit ear vein because of the greater number of collaterals and rapid blood flow caused by the thermoregulatory nature of the ear
One randomized, double-blind, placebo-controlled trial found no evidence that a daily antioxidant supplement containing 12 mg of -carotene, 500 mg of vitamin C, and 400 mg of vitamin E, when taken for up to 12 months, improved mental performance in elderly people (163)
For gut health and barrier function research, once-daily use is often enough, though twice-daily dosing may provide more consistent effects for acute conditions