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With large surface asperities (surface roughness, surface projections), air is trapped between textured grooves, creating air pockets between liquid and surface and dramatically reducing the fraction of surface-liquid contact (Cassie-Baxter state) [5]

doi: 10.1007/s12298-020-00777-3 46 Navari-IzzoF.QuartacciM

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Creatine is crucial for energy production within the cells