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This gap is due to issues in designing nanoparticles, size and shape control, stability over a long period, and immunogenicity of the nanoparticles

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doi: 10.3389/fpls.2016.00838 210 MarucciL.BarberisM.KarrJ.RayO.RaceP

Its decline accelerates the sarcopenic process that estrogen withdrawal initiates, reducing the metabolically active tissue that both burns energy at rest and supports functional independence in later life