Novel Ferroptosis Inhibitors with Improved Potency and ADME Properties
Et godt sted at starte er at forst, hvordan krav til omstning fungerer, hvilke spil der bidrager fuldt ud, og hvordan tidsfrister er udformet
Chronic elevation of these free radicals will deplete GSH/GSSG redox/antioxidant capacity, allowing unopposed free-radical generation and a self-perpetuating cycle, leading to chronic oxidative stress and damage
Reid J, Rana K, Segel SA, Sheikh-Ali M, Choksi RR, Goldfaden RF
The use of antioxidants such as glutathione during chemotherapy or radiation therapy is controversial and probably not recommended [6]
This hypothesis, however, remains speculative and requires prospective validation in appropriately designed trials