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At doses ranging from 40 to 200 mg taken twice daily, the highest weight reduction achieved was up to 11.7% compared to a 1.4% weight increase in the placebo group

Possibly, similar mechanisms are involved in the current in vivo study

Though many are close to the finish line with efficacy and oral delivery, one that eliminates the gastro side-effects has yet to be seen

To put that in perspective, the approved GLP-1 drugs achieved less weight loss in longer timeframes: for example, semaglutide (Wegovy) averages about 15% weight loss over ~16 months, and tirzepatide (Zepbound) achieved around 22.5% at 72 weeks in trials

If you believe you have developed these symptoms after starting Ozempic, it is important to speak with your health care provider to discuss potential treatment options