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Specifically, BACE1 is the enzyme that initially chops the amyloid precursor protein (APP) into a form that then undergoes subsequent processing into neurotoxic A40 and A42 oligomers
Semaglutide is associated with increased neoplasm and tumorigenesis, specifically in the thyroid, bladder, colorectal, and pancreas
Skipping meals or cutting calories too drastically can cause dips in blood sugar that may lead to headaches or even migraines
The GLP-1 receptor agonist liraglutide (brand name Saxenda) was FDA-approved for chronic weight management in 2014
Both share GI-dominant side effects, and head-to-head data showed broadly comparable tolerability
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