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The glucagon receptor assists in regulating blood glucose and potentially boosts energy expenditure by increasing metabolic rate

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Methods: Seven databases were searched until June 2021 for randomized controlled trials with a duration of at least 12 weeks, evaluating the effects of combination therapy with glucagon-like peptide-1 receptor agonists and sodium-glucose co-transporter-2 inhibitors

Research indicates that Semaglutide can help stabilize GFR decline, which is important for slowing the progression of kidney disease