Evidence and Guidance Glucagon-like peptide-1 (GLP-1) receptor agonists, including semaglutide and liraglutide, are increasingly prescribed for type 2 diabetes and weight management in the UK
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doi.org Prescriber / Wiley NICE recommends semaglutide for managing obesity
The trial demonstrated a 20% reduction in the primary composite endpoint of cardiovascular death, nonfatal heart attack, or nonfatal stroke (hazard ratio 0.80, 95% CI 0.72-0.90)
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
Kidney Stress Acute kidney injury has been reported, typically in patients who experienced severe vomiting or diarrhea that led to significant dehydration
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