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[17] Additionally, local IGF-1 production in peripheral tissues may contribute to paracrine and autocrine signaling that supports tissue-specific growth and repair mechanisms
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Although rare, serious side effects have been noted, with gallbladder disease and pancreatitis among the most concerning
By modulating the NO pathway, it can enhance vasodilation, thereby improving blood flow to injured tissues
So, by muting that signal too aggressively, NSAIDs can lead to weaker tissue repair [1, 5]
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