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Both treatment groups were instructed to take 1 tablet in the morning on an empty stomach with up to 120 mL of water and to wait at least 30 minutes before taking food, drink, or other oral medications

b , Quantification of IHC of Smurf1, p-Akt (T308) and Ki-67 of colon tissues from Kras G12D/+ Villin-Cre and the control mice by Image-Pro Plus 6 (n = 3 mice)

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