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Thats really one that I dont know if thats true, but its a big concern in the back of my mind every time someone asks me about that
However, a very small percentage of B12 from a supplemental dose is absorbed by passive diffusion, rather than by intrinsic factor, such that vegans can make up for taking B12 only once per day, or even only once per week, by taking larger doses than normally provided by food
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