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Hypoxia-inducible factor-1 is the therapeutic target of the SGLT2 inhibitor for diabetic nephropathy

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The term "C 1-6 -alkanol", "C 1-6 -alkenol" or "C 1-6 -alkynol", as used herein, alone or in combination is intended to include those C 1-6 -alkane, C 1-6 -alkene or C 1-6 -alkyne groups of the designated length in either a linear or branched or cyclic configuration whereto is linked a hydroxyl (-OH) (cf

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4 Similarly, in tirzepatides SURMOUNT-1 study, 9-15% lost less than 5% and 16-31% loss less than 10% (dose-dependent)