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Prokinetic agents offer pharmacological enhancement of gastric emptying, though efficacy in GLP-1 RA patients varies by agent [62]

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2c) but it is notable that the inhibitory effect of GLP-1(736) (10 pmol/l) was reduced by exendin(939), indicating that part of GLP-1(736)s action is mediated by GLP-1R (possibly via stimulation of somatostatin secretion

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Methods Cell culture, expression constructs, and transfection MIN-6 (purchased from ATCC) cells and GLUTag cells (obtained from Takashi Tsuboi, the university of Tokyo, Japan) were cultured in DMEM with 10% (v/v) heat-inactivated fetal bovine serum

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