54 MartiniC.SaeedZ.SimeoneP.PalmaS.RicciM.ArataA.et al (2025)
246 Notably, HDAC inhibitors (HDACis) exert context-dependent effects and can enhance protective autophagy in tumors while suppressing maladaptive autophagy in cardiac hypertrophy
[197] [214] This internalization is mediated by RhoA activation and its downstream effector ROCK, a process that is TAAR1-dependent
[24] [25] It's important to note that while both medications can affect lipid parameters, large clinical trials (AIM-HIGH and HPS2-THRIVE) have not demonstrated cardiovascular outcome benefits from adding niacin to statin therapy
However, high doses may not provide extra benefits and should be avoided
4c) exhibited an ultrahigh specific surface area of 2162.89 m 2 /g 77 , with mesopore channels (24 nm) effectively reducing the Warburg coefficient to 35, indicating significantly enhanced ion diffusion rates that supported a capacity retention of 98.04 mAh/g at 10 mA/cm 2