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GraphPad Prism (version 10.3.1) was used to produce a dose-response curve and determine the IC 50

Random-effect model and meta-regression analysis were accordingly used

This dual action produces superior weight loss outcomes in clinical trials, with nausea rates ranging from 24% to 40% depending on dose in the SURMOUNT-1 trial

33 Interestingly, many clinical studies have demonstrated that the administration of GLP-1 RAs produces a rapid, substantial and dose-dependent reduction in epicardial adipose tissue thickness

Through the p62Keap1NRF2 pathway, NRF2 upregulates the expression of genes involved in iron and ROS metabolism, such as NQO1 , HO1 , and FTH1 , thereby suppressing ferroptosis (99)

Mix the doses well in the beginning Usually, when you order your MT2 in vials, it will come as a lyophilized powder