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Most preclinical trials used weight-adjusted dosing (mg/kg) that doesn't translate directly to fixed human protocols
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Winkler U et al
However, generally excreted does not mean entirely without consequence. Emerging research has raised questions about whether chronically elevated serum B12 levels may serve as a marker for underlying conditions or could be associated with certain health concerns
They examine its role in cell migration, cytoskeletal organization, and extracellular matrix remodeling
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