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GLP-1 secretion is increased by inflammatory stimuli in an IL-6-dependent manner, leading to hyperinsulinemia and blood glucose lowering
PMID: 41187492
There is no valid dose conversion between these compounds
This treatment should be provided within specialist weight management services, is typically time-limited (generally up to 2 years), and must be part of a comprehensive programme including dietary modification, increased physical activity, and behavioural support
Indeed, many original investigations, summarized in later review [4], indicated that LC supplementation lasting up to 4 weeks, neither increase fat oxidation nor improve performance during prolonged exercises