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The cells of people with male pattern baldness have been shown to be more susceptible to oxidative stress than average, according to Upton et al
We have also demonstrated that GPX4 is highly expressed in some thyroid cancer cell lines
Overexpression of F3H in rice enhanced quercetin and kaempferol biosynthesis under salinity stress (Jan et al., 2021), while SIbHLH22 overexpression in tomato promotes flavonoid accumulation under drought and salinity stress, albeit with developmental trade-offs such as reduced plant height and smaller leaves (Waseem and Li, 2019)
Interestingly, an antagonist of MC-4R had an opposite effect, suggesting that MC-4R activation by MT-2 influences preference for alcohol
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