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Dysbiosis, characterized by an imbalance of beneficial and harmful microbes, may contribute to inflammation, DNA damage, and tumorigenesis in the colon

Clinical trials and patient experiences have demonstrated that a significant weight reduction can be achieved within a few months of starting treatment

Bonnans C, Chou J, Werb Z

JACC Asia 2 , 287293 (2022)

These drugs are part of an emerging class of nutrient-stimulated hormone-based therapeutics that act as incretin mimetics, targeting G-proteincoupled receptors such as GLP-1, glucose-dependent insulinotropic polypeptide (GIP), and glucagon, which are crucial in body fat and energy balance regulation