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Large-scale cardiovascular outcome trials have not identified increased fracture incidence with semaglutide compared to placebo or other diabetes treatments

Psilocybin therapy increases cognitive and neural flexibility in patients with major depressive disorder

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Green JB, Bethel MA, Armstrong PW et al (2015) Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes

Both are generally well-tolerated

Keep it refrigerated at 3646F (28C) and protected from light