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In order to enhance the clinical interpretation of these CVOTs, researchers have quantified the absolute treatment effect over time based on the number of treatments required to avoid a MACE, thus revealed the difference between GLP-1RA [175]
Furthermore, they also found that 'a balanced dual agonist in mice engineered to lack GLP-1 receptors still induced weight loss, proving that the compounds were not causing weight loss purely by targeting GLP-1' (Molteni, Chen)
It also supports the production of lymphocytes, which are important for a strong immune response
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Endocrinology 141 (1), 111117
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