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FDA did not find evidence of such a link

Participants who switched from Tirzepatide to placebo regained substantial weight over the following year

Copaescu AM, Trubiano JA

Anti-diabetics encompass a wide range of drug classes, including biguanides, sulfonylureas, thiazolidinediones, dipeptidyl peptidase-4 (DPP-4) inhibitors, sodium-glucose cotransporter-2 (SGLT2) inhibitors, and glucagon-like peptide-1 (GLP-1) receptor agonists