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However, the role of nutritional supplements in CIPN remains controversial due to the varied mechanisms of neuropathy induced by different antineoplastic drugs and the presence of complex drug interactions, and further research on such drugs is necessary in the future
Given 40-60% nasal bioavailability compared to 80-95% for injection, equivalent nasal doses would be approximately 400-1000mcg to achieve similar systemic levels
J., Klein, S
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PDR for Nutritional Supplements
Schadendorf, A.C.J
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