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Metabolomic changes and polyunsaturated fatty acid biosynthesis during gonadal growth and development in the sea urchin Strongylocentrotus intermedius

Biochem Genet 19(11-12):1237-45, 1981

Conclusions A high index of suspicion for hyperammonaemia is mandatory in paediatric patients of any age with suggestive clinical symptoms, given that almost all survivors have developmental disabilities that correlate with the number, severity and duration of hyperammonaemic episodes

While at-home administration is possible with a prescription and guidance from a qualified medical professional, self-medicating comes with substantial risks

Typical protocols involve doses ranging from 13 mg daily or several times per week, often cycled in 812 week intervals with breaks to prevent receptor downregulation or potential copper accumulation

PMID 20536453