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Beukes EW, Manchaiah V, Andersson G, Allen PM, Terlizzi PM, Baguley DM

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Testosterone acts through androgen receptors in osteoblasts, while IGF-1 stimulates osteoblast proliferation and bone matrix synthesis (9)

A typical timeline from a Nature preclinical paper of this caliber to FDA approval, for drug classes with established regulatory paths, is seven to twelve years